TGsol (Translational Genomics for Solanaceae)

TGsol (Translational Genomics for Solanaceae) is the specialized web interface providing the integrated view of genomic big-data available to practical breeding process of Solanaceae crop. TGsol will play important role as a bridge between genomic evidence and molecular breeding via supporting to effective communication and utilization.

VISION (Aims)

¡¤ Sharing the Genomic big-data
¡¤ Integrating front (genome) industry and rear (breeding) industry (market)
¡¤ Invigorating BREEDING ¡¤ SEED industry

TGsol Function (Summary)

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Target Crop: Solanaceae crop (Tomato, Pepper and Potato)
Main Function : Genome browser, Breeding supporting viewer (MAB, MAS), Comparative analysis tool (viewer), BLAST
Application : TGsol provide re-processed and re-interpreted information desired for marker-assisted breeding process.

Genome browse

Genome browser display detailed gene information in chromosome view of reference genome.

Process

¡¤ Gene and protein sequence (User can customize region of desired sequence)
¡¤ Gene annotation with various database
¡¤ SNP marker information

MAB (Marker-assisted backcrossing)

To facilitate MAB in a practice breeding program, we developed a program providing selected markers for background selection from genome-wide SNPs in resequencing, transcriptome data sets.

Process

¡¤ Markers provided depending on cross combination.
¡¤ Marker set accordance with distance of physical or genetic
¡¤ Primer designed for SNP marker detection

MAS (Marker-assisted selection)

TGsol offer trait-related gene information desired for MAS (maker-assisted selection) using genome, gene, and SNP marker sequence.

Process

¡¤ Target genes for disease resistance
¡¤ Target genes for fruits development
¡¤ Target genes for useful metabolites.

Comparative analysis

Comparative analysis tool is a web-based genome viewer to identify orthologous genes based synteny as well as sequence similarity between tomato, pepper, and potato genome. The tool has a step-by-step interface with multiple viewing levels to support easy exploration for candidate ortholog of target gene.

Process

¡¤ Search for candidate orthologs of target gene
¡¤ Viewer for exploring the orthologs of target gene (Whole-genome, chromosome, Synteny block view)
¡¤ Link to the SNP database for marker development